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Dr. Marcello Deraco
U.O. Melanoma e Sarcoma
Istituto Nazionale Tumori Milano
Via Venezian 1
20133 Milano, Italia
www.marcelloderaco.com
info@marcelloderaco.com
Tel/ Fax: +39.02.76008435

CURRICULUM VITAE

Hospital Address Department of Surgery, Melanoma and Sarcoma Unit, National Cancer Institute of Milan , Via Venezian, 1 - 20133 Milan Italy

Telephone/ Fax +39 02 76008435
+39 335-247236 ( Mobile )
E-mail marcelloderaco@hotmail.com
Web page www.marcelloderaco.com

Education
High School Vincenzo Guerrisi High School Cittanova, RC Italy 1981
Medical Doctor University of Messina , Italy July 1987
General Surgery University of Messina , Italy October 1992
Oncology University of Paris IX, France 1993

Clinical Experience
Associated Researcher Dept. of Surgery at the "National Cancer Institute of Milan ", Italy

1989-1991/1994-1998
Associated Researcher Dept. of Surgery at the "Gustave Roussy Institut" Villejuif , France

1991-1993
Associated Researcher Dept. of Surgery at "The Royal Marsden Hospital " London , UK

1993
Visiting MD Dept. of Surgery "Washington Cancer Institute at the Washington Hospital Center ", Washington DC USA

1996
Current Position : Attending Surgeon Department of Surgery Melanoma and Sarcoma Unit at the National Cancer Institute of Milan , Italy

Membership and Secretary SITILO Società Italiana di Terapie Integrate Loco-Regionali in Oncologia (Italian Society for Loco Regional Cancer Therapy)

Membership
SIC Società Italiana di Chirurgia
SICO Società Italiana di Chirurgia Oncologica
ISRCT International Society for Regional Cancer Therapy

Licensure European Community

Dr. Marcello Deraco

Participation in National Protocols at the National Cancer Institute of Milan

  • "Evaluation of cytoreductive surgery (peritonectomy) and intra peritoneal hyperthermic perfusion in patients affected by pseudomyxoma peritonei or mesothelioma. A phase II clinical study". Study of AIRC 1998-2000.
  • "Intra Peritoneal Hyperthermic Perfusion with Doxorubicin and cis-Platin. A multicentric phase I Clinical Study".
  • "Primary Chemotherapy for Locally advanced Gastric Carcinoma".
  • "Treatment of locally advanced gastric cancer by radical surgery and intra peritoneal hypertermic perfusion. A multicentric phase II clinical study."
  • "Stop-Flow perfusion with Adryamicin + Mitomycin C in the treatment of rectal cancer recurrence. Phase II clinical study."
  • "Intergrups Italian Study, Non resectable pancreatic cancer: Systemic Chemotherapy with 5-FU vs Systemic Chemotherapy with Gemcitabin vs Loco-Regional Chemotherapy with FLEC. A multicentric SITILO randomised clinical study."
  • "A Phase I/II study of active specific immunotherapy in patients with metastatic melanoma using autologous tumor-derived, Heat Shock Protein Peptide Complex-96 (HSPPC-96), vaccine."
  • Innovative treatment of peritoneal mesothelioma: translational and clinical study. Studio finanziato dall'AIRC n° 47/01/18
  • Valutazione della peritonectomia e della perfusione ipertermicain pazienti con pseudomixoma del peritoneo o mesotelioma: studio di fase II. Ministero della Sanità-Ricerca Corrente IRCCS- Nuove frontiere della chirurgia oncologica e della riabilitazione n° progetto 7.13
  • Stage III / IV epithelial ovarian cancer with macroscopic residual disease after 1 st line Chemotherapy: a multicentric prospective randomised study comparing loco regional approach + systemic chemotherapy vs systemic chemotherapy alone
  • (CIPOV)
  • Analysis of survival and biological markers in peritoneal mesothelioma managed with an innovative treatment AIRC Grant 2005-07

LIST OF PUBLICATIONS

  1. Famulari, A. Caratozzolo, C. Mastrojeni, G. Mazzeo, M. Deraco: Programma di sorveglianza delle trombosi venose profonde post-operatorie. Acta Chirurgica Italica 1989; Vol. 45, fasc. 1.
  2. Elias, Ph. Lasser, A. Leroux, Ph. Rougier, M.G. Comandella, M. Deraco: Colostomies périnéales pseudo-continentes après amputation rectale pour cancer. Gastroenterol Clin Biol 1993; 17: 181-186.
  3. R. Cavaliere, F. Cavaliere, M. Deraco, F. Di Filippo, M. Santinami, S. Monica, A. Michele and M. Vaglini: Hyperthermic antiblastic perfusion in the treatment of stage IIIA-IIIAB melanoma patients. Comparision of two experiences. Melanoma Research 1994; 4(Suppl. 1): 5-11.
  4. Santinami, F. Belli, N. Cascinelli, O. Carraro, B. Damascelli, M. Deraco, F. Gallino, R. Manzi, L. Persiani, N. Santoro and M. Vaglini: Regional perfusion in the treatment of locally advanced pelvic cancer. Reg. Cancer Treat. 1994; Vol. 7(1): 33-38.
  5. Elias D., Ducreux M., Rougier Ph., Comandella M.G., Deraco M., Doydy L., Lasser Ph.: Chimiothérapie intra-arterielle hépatique. Expérience de 200 cas. Gastroenterol Clin Biol 1994; 18: 975-982.
  6. Panté, S. Perri, V. Lepore, F. De Jesi, A. Napoli, G. Leonello, M. Deraco: La nostra esperienza nella profilassi della P.A.P.O. con Somatostatina. Estratto degli atti della Società Siciliana di Chirurgia.
  7. Vaglini, F. Belli, O. Carraro, M. Deraco, L. Mascheroni, L. Persiani, A. Prada, N. Santoro and M. Santinami: Regional perfusion for osteogenic sarcoma of extremities. Long term results for limb salvage in primary advanced disease and local control in presence of long metastases. Reg. Cancer Treat 1994; Vol. 7(2): 106-110.
  8. Vaglini, O. Carraro, F. Belli, F. D'Elia, M. Deraco, L. Persiani, N. Santoro, M. Santinami: Alfa TNF + L-PAM for stage IIIA-IIIAB extremities melanoma. European Journal of Surgical Oncology 1994; 20(3): 322.
  9. Vaglini, O. Carraro, V. Costagli, M. Deraco, L. Persiani, N. Santoro and M. Santinami: Limb salvage by Isolated Limb Perfusion with TNF and Melphalan for non resectable recurrent Soft Tissue Sarcoma (STS). International Congress on Regional Cancer Treatment. Eilat August 30, 1994.
  10. Deraco M., Vaglini M., Santinami M., Costagli V., Di Re F., Inglese M.G., Mascotti G., Persiani L., Santoro N., Sequeira C., Carlier Somers D.: Razionale per un trattamento chemioterapico della carcinosi peritoneale. Argomenti di Oncologia 1995; 16(2): 149-159.
  11. Vaglini M., Deraco M., Santinami M., Di Re F., Inglese M.G., Manzi R., Persiani L., Santoro N., Sequeira C., Sala B., Carlier Somers D., Stefanon B.: Chemioipertermia intraperitoneale: Tecnica chirurgica. Argomenti di Oncologia 1995; 16(2): 161-167.
  12. Rougier Ph, Ducreux M, Elias D, Comandella MG, Deraco M, Lasser Ph.: Indications of intra arterial hepatic chemotherapy (I A H C) for liver metastatic (LM) from colorectal cancer (CRC). Reg. Cancer Treat. suppl. 1: 42-43.
  13. Elias, M. Comandella, M. Deraco, M. Ducreux, Ph. Lasser, Ph. Rougier: La chemioterapia intra-arteria epatica (196 casi): una terapia in progresso. Estratto degli atti del 95° Congresso della Società Italiana di Chirurgia.
  14. Vaglini M., Chiti A., Cistagli V., Deraco M., Inglese M.G., Persiani L., Santoro N., Santinami M.: Limb salvage by isolated-perfusion using -TNF and melphalan for extremities’ soft tissue sarcoma. Atti del “Fifth International Congress on Anti-Cancer Chemotherapy” - Parigi, 31 gennaio - 3 febbraio, 1995.
  15. Santinami M., Carraro O., Manzi R., Persiani L., Santoro N., Seregni E., Vaglini M., Deraco M.: Preliminary results of primary or recurrent pelvic cancer treated by isolated pelvic perfusion. Atti del “Fifth International Congress on Anti-Cancer Chemotherapy” - Parigi, 31 gennaio - 3 febbraio, 1995.
  16. Vaglini M., Azzarelli A., Carraro O., Chiti A., Deraco M., Persiani L., Rizzi M., Santoro N., Santinami M.: Preliminary results of -TNF + L-PAM in stage IIIA-IIIAB melanoma and non resectable soft tissue sarcomas of extremities. Atti del 31° Meeting Annuale ASCO - 20-23 Maggio, 1995; Vol. 14: 416.
  17. Vaglini, F. D’Elia, M. Deraco, M.G. Inglese, L. Persiani, N. Santoro and M. Santinami: Isolated limb perfusion for treatment of stage IIIA-IIIAB melanoma; comparision of two different approach. Advances in the Biology and Clinical Management of Melanoma. February 21-24, 1995; Thirty-eighth annual clinical Conference.
  18. Vaglini M., Santinami M., Chiti A., Costagli V., Deraco M., Inglese M.G., Parmiani G., Santoro N., Arienti F.: Treatment of in-transit metastases (IIIA-IIIAB) by isolated perfusion with IL2, TNF and lak cells. Atti del convegno “Innovative Therapies in Cancer Treatment” - Ravenna, 25-26 Novembre 1995.
  19. Deraco M., Santinami M., Santoro N., Persiani L., Inglese M.G., D’Elia F., Sequeira C., Vaglini M., Cascinelli N.: Treatment of peritoneal carcinosis using hyperthermic intraperitoenal perfusion. Atti della “The European Cancer Conference - ECCO 8”. Eur. J. Cancer 1995; Vol. 31A(Suppl. 5): S111.
  20. Santinami M., Deraco M., Inglese M.G., Manzi R., Persiani L., Santoro N., Sequeira C., Vaglini M., Cascinelli N.: Isolated limb perfusion for stage IIIA-IIIAB melanoma: TNF + L-PAM and L-pam + hyperthermia. Atti della “The European Cancer Conference - ECCO 8”. Eur. J. Cancer 1995; Vol. 31A(Suppl. 5): S47.
  21. Vaglini M., Deraco M., Santoro N., Persiani L., Inglese M.G., Costagli V., Chiti A., Santinami M., Cascinelli N.: Isolated pelvic perfusion for treatment of non-resectable pelvic recurrences. Atti della “The European Cancer Conference - ECCO 8”. Eur. J. Cancer 1995; Vol. 31A (Suppl. 5): S157.
  22. Somers, M. Tournaire, O.F. de Castro, M. Deraco: Diethylstilbestrol (DES) no Brasil. FEMINA, vol. 23, numero 6, pg. 549-554, julho 1995.
  23. Santinami M., Vaglini M., Deraco M., Chiti A., Inglese M.G., Manzi R., Persiani L., Prada A., Rizzi M., Sala B., Santoro N., Sequeira C., Seregni E.: Valutazione dell’efficacia del -TNF associato a L-PAM nel trattamento perfusionale dei melanomi degli arti allo stadio IIIA e IIIAB mediante perfusione ipertermica in circolazione extra-corporea. Argomenti di Oncologia 1995; 16(3): 217-226.
  24. Rossi C.R., Di Filippo F., Santinami M., Foletto M., Vecchiato A., Vaglini M., Azzarelli A., Cavaliere R., Deraco M., Lise M., Quagliuolo V., Schiratti M., Inglese M.G.: Perfusione ipertermico-antiblastica con TNF-Alfa ed adriamicina in pazienti con sarcomi delle parti molli degli arti candidati all’amputazione: risultati preliminari. Argomenti di Oncologia 1995; 16(3): 227-233.
  25. Vaglini M., Santinami M., Deraco M., Azzarelli A., Chiti A., Costagli V., Inglese M.G., Persiani L., Prada A., Quagliuolo V., Rizzi M., Santoro N., Sequeira C.: Trattamento delle recidive non resecabili da sarcoma dei tessuti molli degli arti mediante perfusione ipertermica. Argomenti di Oncologia 1995; 16(3): 241-247.
  26. Santinami M., Vaglini M., Deraco M., Carlier Somers D., Chiti A., Lupi G., Fontanelli R., Galluzzo D., Inglese M.G., Manzi R., Mascotti G., Persiani L., Prada A., Raspagliesi F., Riboldi G., Santoro N., Sequeira C.: Recidive neoplastiche della pelvi: un nuovo approccio chirurgico mediante perfusione isolata ipertermico-antiblastica. Argomenti di Oncologia 1995; 16(3): 253-259.
  27. Rossi C.R., Deraco M., Vaglini M., Inglese M.G., Lise M., Menin N., Persiani L., Santinami M., Santoro N., Vecchiato A., Perego G.: Carcinosi peritoneale: razionale e indicazioni al trattamento chirurgico associato alla chemioipertermia intraperitoneale. Argomenti di Oncologia 1995; 16(3): 307-311.
  28. Deraco M., Vaglini M., Rossi C.R., Santinami M., Carlier Somers C., D’Elia F., Lupi G., De Palo G., Fontanelli R., Inglese M.G., Lise M., Perego G., Persiani L., Raspagliesi F., Oriana R., Santoro N.: Trattamento della carcinosi peritoneale mediante chemio-ipertermia intra peritoneale. Risultati preliminari. Argomenti di Oncologia 1995; 16(3): 313-318.
  29. Vaglini M., Costagli V., Deraco M., Inglese M.G., Persiani L., Santoro N., Santinami M.: Treatment of non resectable recurrent soft tissue sarcoma (STS) of extremities with isolated limb perfusion + TNF and melphalan. Atti del “48° Cancer Symposium della SSO - Boston, 23-26 Marzo 1995”.
  30. Deraco M., Vaglini M., Santinami M., Vecchiato A., Lise M., Santoro N., Persiani L., Inglese M.G., Sequeira C., Costagli V., Di Re F., Rossi C.R.: Preliminary results of intra peritoneal hyperthermic perfusion for patients with peritoneal carcinosi. Atti della “VII International Conference on Regional Cancer Treatment” 11-13 Settembre 1995 - Wiesbaden, Germany.
  31. Santinami M., Chiti A., Deraco M., Inglese M.G., Manzi R., Persiani L., Sequeira C., Santoro N., Vaglini M.: Does TNF improve complete responses in perfusion of IIIA-IIIAB limb’s melanoma? Atti della “VII International Conference on Regional Cancer Treatment” 11-13 Settembre 1995 - Wiesbaden, Germany.
  32. Vaglini M., Deraco M., Chiti A., Costagli V., Inglese M.G., Persiani L., Prada A., Santoro N., Sequeira C., Santinami M.: Current results of pelvic perfusion for non resectable or relapsing pelvic cancer. Atti della “VII International Conference on Regional Cancer Treatment” 11-13 Settembre 1995 - Wiesbaden, Germany.
  33. Raspagliesi F., Deraco M., Santinami M., Vaglini M., Inglese M.G.: Chirurgia e chemioterapia endoperitoneale in ipertermia nel trattamento dei tumori ovarici. Atti della Società Italiana di Ginecologia e Ostetricia, Firenze - 29 settembre / 2 ottobre 1996; pagg. 439-444.
  34. Santinami M., Deraco M., Azzarelli A., Cascinelli F., Chiti A., Costagli V., Inglese M.G., Manzi R., Quagliolo V., Rebuffoni G., Santoro N., Vaglini M.: Treatment of recurrent sarcoma of the extremities by isolated limb perfusion using tumor necrosis factor alpha and melphalan. Tumori 1996; 82: 576-581.
  35. Vaglini M., Cascinelli F., Chitit A., Deraco M., Inglese M.G., Rebuffoni G., Rizzi M., Sala B., Santoro N., and Santinami M.: Isolated pelvic perfusion for the treatment of unresectable primary or recurrent rectal cancer. Tumori 1996; 82: 461-464.
  36. Deraco M., Vaglini M., Santinami M., Santoro N., Inglese M.G., and Spatti G.B.: Intraperitoneal hyperthermic perfusion (IPHP): Analysis of morbidity and toxicity. Oncology Reports 1996; 3: 1103-1106.
  37. Santinami M., Cascinelli F., Chiti F., Galluzzo D., Inglese M.G., D’Elia F., Santoro N., Sequeira C., Vaglini M., and Deraco M.: Current results of pelvic perfusion for non resectable relapsing of pelvic cancer. Oncology Reports 1996; 1097-1102.
  38. Vaglini M., Deraco M., Santinami M.: Isolated pelvic perfusion for the treatment of non resectable primary or recurrent rectal cancer. PANMINERVA MED. 1996; 38 (suppl. 1 to No. 2): 48.
  39. Vaglini M., Deraco M., Inglese M.G., Maucione A., Santoro N., Bozzetti F.: Nuove prospettive terapeutiche del carcinoma gastrico mediante l'uso di trattamenti innovativi. Argomenti di Oncologia 1997; 18 (2): 105-113.
  40. Vaglini M., Deraco M., Santoro N., Inglese M.G., Rebuffori G.: Current results of pelvic perfusion for non resectable relapsing of pelvic cancer. J. Exp. Clin. Cancer Res., 16, 2, 1997; 112.
  41. Vaglini M., Deraco M., Santoro N., Inglese M.G., Rebuffoni G.: Current results of pelvic perfusion for non-resectable relapsing of pelvic cancer. 21st National Congress of the Italian Society of Surgical Oncology (SICO) - June 26-28, 1997 -San Felice Circeo. J Exp. Clin. Cancer Res. 16 (suppl.), 2: 112.
  42. Vaglini M., Deraco M., Santoro N.: Trattamento ipertermico antiblastico delle carcinosi peritoneali. Convegno Internazionale “L’Approccio Globale al Paziente Oncologico”, Castrocaro Terme - 17-19 aprile ’97. Quaderni di Cure Palliative 1997; Vol. 5 (SI): 16.
  43. Vaglini M., Rossi C.R., Santoro N., Inglese M.G., Carraro O., Deraco M.: Intraperitoneal hyperthermic perfusion (IPHP) in the treatment of peritoneal carcinomatosis: Italian experience. 8th International Conference of Regional Cancer Treatment: “Regional Therappy of Cancer - The Future”, Ulm (Germany), 20-22 ottobre ’97. Reg. Cancer Treat. 1997; Suppl. 1: S4.20.
  44. Deraco M., Santoro N., Inglese M.G., Sequeira C., Azzarelli A., Vaglini M.: Complete peritonectomy and intra peritoneal hyperthermic perfusion in the treatment of pseudomyxoma peritonei. Experience at the National Cancer Institute of Milan. 8th International Conference of Regional Cancer Treatment: “Regional Therappy of Cancer - The Future”, Ulm (Germany), 20-22 ottobre ’97; Reg. Cancer Treat. 1997; Suppl. 1: P4.23.
  45. Deraco M., Santoro N., Inglese M.G., Moneta A. and Vaglini M.: Evaluation of Tissue Oxygen Partial Pressure (ptiO2) in patients treated by Isolated Limb Perfusion (ILP). 8th International Conference of Regional Cancer Treatment: “Regional Therappy of Cancer - The Future”, Ulm (Germany), 20-22 ottobre ’97; Reg. Cancer Treat. 1997; Suppl. 1: P2.05.
  46. Deraco M., Azzarelli A., Santoro N., Inglese M.G., Maucione A., and Vaglini M.: Treatment of recurrent sarcoma of the extremities by isolated limb perfusion: comparison of different schedules of treatment. 8th International Conference of Regional Cancer Treatment: “Regional Therappy of Cancer - The Future”, Ulm (Germany), 20-22 ottobre ’97; Reg. Cancer Treat. 1997; Suppl. 1: S2.14.
  47. Vaglini M., Santoro N., Inglese M.G., Rebuffoni G., and Deraco M.: Current results of pelvic perfusion for non-resectable relapsing of pelvic cancer. 8th International Conference of Regional Cancer Treatment: “Regional Therappy of Cancer - The Future”, Ulm (Germany), 20-22 ottobre ’97; Reg. Cancer Treat. 1997; Suppl. 1: S6.14.
  48. Vaglini M., Deraco M.: Intra Peritoneal Hyperthermic Perfusion in the treatment of advanced ovarian cancer. Congresso “Breast and ovarian cancer: Molecular markers of risk, progression and new therapeutic strategies”, Pisa - 25-27 settembre ’97.
  49. Gomes Portilla A., Deraco M., Sugarbaker P.H.: Clinical Pathway for Peritoneal Carcinomatosis from Colon and Rectal Cancer: Guidelines for Current Practice. Tumori 1997; Vol. 83 (4): 725-728.
  50. Vaglini M., Azzarelli A., Inglese M.G., Rebuffoni G., Santoro N., Deraco M.: Treatment of recurrent soft tissue sarcoma of the extremities by isolated limb perfusion: comparison of different schedules of treatment. Abstract book del 17th International Cancer Congress. Rio de Janeiro, 23-28 agosto 1998, p. 198.
  51. Deraco M., Santoro N., Inglese M.G., Maucione A., Azzarelli A., Mazzaferro V., Vaglini M.: Pseudomyxoma peritonei: impact of primary histology on potentially radical treatment. Abstract book del 17th International Cancer Congress. Rio de Janeiro, 23-28 agosto 1998 - p. 198.
  52. Deraco M., Santoro N., Inglese M.G., Carlier Somers D., Carraro O., Vaglini M.: Could advanced ovarian cancer be responsive to cytoreductive surgery and intraperitoneal hyperthermic perfusion? Abstract book del 17th International Cancer Congress. Rio de Janeiro, 23-28 agosto 1998 - p. 199.
  53. Bozzetti F., Vaglini M., Deraco M.: Intraperitoneal hyperthermic chemotherapy in gastric cancer: rationale for a new approach. Tumori 1998; Vol. 84 N. 4: 483-488.
  54. Guadagni S., Pistoia M.A., Valenti M., Leocata P., Coletti G., Calvisi G., Madonna R., Deraco M., Reed P.I.: N-Nitroso compounds, bacteria, and carcinoembryonic antigen in the gastric stump. J. Surg. Res. 1998 Dec.; 80 (2): 345-51.
  55. Guadagni S., Aigner K.R., Palumbo G., Cantore M., Fiorentini G., Pozone T., Deraco M., Clerico M., Chaudhuri P.K.: Pharmacokinetics of Mitomycin C in pelvic stopflow infusion and hypoxic pelvic perfusion with and without hemofiltration: a pilot study of patients with recurrent unresectable rectal cancer. J. Clin. Pharmacol. 1998; Vol. 38 N. 1: 936-944.
  56. Deraco M., Santoro N., Carraro O., Inglese M.G., Rebuffoni G., Guadagni S., Carlier Somers D., Vaglini M.: Peritoneal Carcinomatosis: Features of dissemination. Review. Tumori 1999; Vol. 85 N. 1: 1-5.
  57. Guadagni S., Pistoia M.A., Amicucci G., Leocata P., Ventura L., Ventura T., Chiominto A., Deraco M., Vaglini M.: N-Nitroso compounds, and helicobacter pylori in the gastric remnant. Tumori 1999; Vol. 85 N. 2: 108-112.
  58. Vaglini M., Azzarelli A., Inglese M.G., Rebuffoni G., Santoro N., Santoro N., Deraco M.: Treatment of recurrent soft tissue sarcoma of the extremities by isolated limb perfusion: Comparison of different schedules of treatment. J. Surg. Oncol. 1999; 70 (2): 143.
  59. Deraco M., Santoro N., Inglese M.G., Carlier Somers D., Carraro O., Vaglini M.: Could advanced ovarian cancer be responsive to cytoreductive surgery and intraperitoneal hyperthermic perfusion? J. Surg. Oncol. 1999; 70 (2): 135-136.
  60. Santinami M., Deraco M., Inglese M.G., Santoro N., Vaglini M.: Regional treatment of locally advanced melanoma. Abstract of the International Congress: Clinical Dermatology 2000 Vancouver.
  61. Ducreux M., Rougier Ph, Elias D., Fabri M.C., Kac J., Pignon J.P., Tigaud J.M., Bognel C., Commandella M.G., Deraco M., Lasser Ph.: Metastases hepatiques (MH) de cancers colo-rectaus (CCR) traitees par chimiotherapie intra-arterielle hepatique (CIAH): Facteurs prognostiques et survies (S) prolongees. Abstract delle Journees Francophones de Pathologie Digestive, Paris 19-23 marzo 1994.
  62. Rossi R.C., Pilati P.L., Mocellin S., Vaglini M., Deraco M., Lise M.: Carcinoma dell’ovaio : studio pilota sulla perfusione ipertermico-antiblastica intraperitoneale intraoperatoria. Tumori 1999; Vol. 85 N.3 Suppl. 1: 43-45.
  63. Di Filippo F., Rossi C.R., Vaglini M., Azzarelli A., Anza M., Santinami M., Lise M., Cavaliere F., Giannarelli D., Quagliuolo V., Vecchiato A., Deraco M., Garinei R., Foletto M., Botti C., Cavaliere R.: Hyperthermic antiblastic perfusion with alpha tumor necrosis factor and doxorubicin for the treatment of soft tissue limb sarcoma in candicates for amputation: results of a phase I study. J.Immunotherapy 1999; Vol. 22 (5): 407-414.
  64. Vaglini M., Santoro N., Inglese M.G., Carlier Somers D., Guadagni S., Carraro O., Deraco M.:Treatment of advanced ovarian cancer by cytoreductive surgery associated with intra peritoneal hypertermic perfusion. European Journal of Cancer 1999; Vol. 35 Suppl. 4: P936.
  65. Deraco M., Santoro N., Inglese M.G., Guadagni S., Maucione A., Azzarelli A., Mazzaferro V., Zanna M., Vaglini M.: Complete peritonectomy associated with intra peritoneal hyperthermic perfusion in the treatment of Pseudomyxoma Peritonei: Experience at the National Cancer Institute of Milan. European Journal of Cancer 1999; Vol. 35 Suppl. 4: P524.
  66. Guadagni S., Marchetti P., Fiorentini G.M., Iaffaioli V., Cantotea M., Deraco M., Vaglini M.: Perfusione Pelvica Ipossodica nel trattamento di pazienti con recidiva non resecabile da carcinoma del retto. Da: «Le recidive pelviche da neoplasia del retto: diagnosi, stadiazione e terapia.»; Basilico L. e Valentini V.: Ed. In Vasto – Arte della Stampa/Cannarsa 191-202.
  67. Guadagni S., Pizzutilli A., Mancini E., Varrone A., Palumbo G., Amicucci G., Perri S., Deraco M., Fiorentini G.: Significance of Duplex/color doppler sonography in hepatic arterial chemotherapy for patients with liver metastases from colorectal carcinoma. Eur. J. Surg. Oncol. 2000; 26 (4): 381-6.
  68. Deraco M, Inglese MG, Guadagni S, Pennacchioli E, Merson M, Santoro N, Kusamura S, Casali P, Vaglini M. Peritonal mesothelioma treated by cytoreductive surgery and intra peritoneal hyperthermic perfusion. ICACT: 10th International Congress on Anti-Cancer Treatment, Paris, 31 gennaio – 3 febbraio 2000.
  69. Vaglini M, Deraco M, Pennacchioli E. Regional Chemotherapy for Solid Tumors. In: Surgical Oncology “Contemporary Principles and Practice” – Kirby I. Bland MD., John M. Daly MD., Constantine P. Karakousis.MD. PhD FACS. McGRAW-HILL Medical Publishing Division
  70. Deraco M., Vaglini M. Chirurgia citoriduttiva (peritonectomia) e chemio ipertermia intra peritoneale: un approccio innovativo ed efficace nel trattamento dello pseudomixoma peritonei. Estratto da Archivio ed atti della Società Italiana di Chirurgia, Roma 15-18 ottobre 2000, Vol. 3°.
  71. Vaglini M., Deraco M., Kusamura S., Raspagliesi F. Chirurgia Citoriduttiva e associata a chemio ipertermia intraperitoneale in pazienti affetti da carcinoma epiteliale ovarico con second-look laparotomico positivo: proposta di studio randomizzato mulcentrico. Estratto da Archivio ed atti della Società Italiana di Chirurgia, Roma 15-18 ottobre 2000, Vol. 3°.
  72. Vaglini M., Deraco M. Mesotelioma peritoneale: approccio terapeutico multinodale mediante chemioterapia sistemica, peritonectomia e chemioipertermia intra peritoneale. Estratto da Archivio ed atti della Società Italiana di Chirurgia, Roma 15-18 ottobre 2000, Vol. 3°.
  73. Kusamura S., Teixeira L.C., dos Santos M.A., Andrade L.A., Campos Torres J.C., Sagarra A., Deraco M., Derchain S.F.M. Ovarian Germ Cell Cancer: clinicopathologic analysis and outcome of 31 cases. Tumori 2000; 86 (6): 450-454.
  74. Guadagni S., Fiorentini G., Palumbo G., Valenti M., Russo S., Cantore M., Deraco M., Vaglini M., Amicucci G.Hypoxic Pelvic Perfusion with Mitomycin C using a simplified balloon-occlusion technique in the treatment of patients with unresectable locally recurrent Rectal Cancer. Arch Surg. 2001; 136:105-112.
  75. Deraco M.., Rossi C.R., Pennacchioli E., Merson M., Carlier Somers D., Santoro N., Kusamura K and Vaglini M., Cytoreductive Surgery and Intra Peritoneal Perfusion in the treatment of recurrent epithelial ovarian cancer: a Phase II clinical Study". Tumori; 2001: Vol. 87: 120-126.
  76. Guadagni S., Russo F., Rossi C.R., Pilati P.L., Miotto D., Fiorentini G., Deraco M., Santinami M., Palumbo G., Valenti M., Amicucci G. Deliberate hypoxic pelvic and limb chemoperfusion in the treatment of recurrent melanoma. Am J Surg; 2002: 183(1): 28-36.
  77. Rossi C.R., Foletto M., Mocellin S., Pilati P., De S.M., Deraco M., Cavaliere F., Palatini P., Guasti F., Scalerta R., Lise M. Hyperthermic intraoperative intraperitoneal chemotherapy with cisplatin and doxorubicin in patients who undergo cytoreductive surgery for peritoneal carcinomatosis and sarcomatosis: phase I study. Cancer 2002: 15(94): 492-499.
  78. Di Filippo F., Cavaliere F., Anzà M., Garinei R., Rossi C.R., Deraco M., Perri P., Botti C., Cigna E. Hyperthermic - antibalstic perfusion in the treatment of tumor of the extremities. Review. Tumori 2002: suppl. 1 (3): S35-A37.
  79. Deraco M., Gronchi A., Mazzaferro V., Inglese M.G., Pennacchioli E., Kusamura S., Rizzi M., Anselmi Jr. R.A., Vaglini M. Feasibility of Peritonectomy associated with Intra Peritoneal Hyperthermic Perfusion in patients with Pseudomixoma Peritonei. Tumori 2002: 88 (5): 370-5.
  80. Deraco M., Casali P., Inglese M.G., Baratti D., Pennacchioli E., Bertulli R., Kusamura S. Peritoneal Mesothelioma treated by Induction Chemotherapy, Cytoreductive Surgery and Intraperitoneal Hyperthermic Perfusion. J Surg Oncol. 2003 Jul;83(3):147-53.
  81. Deraco Marcello, MD, Raspagliesi Francesco MD, and Kusamura Shigeki MD, Management of peritoneal surface component of ovarian cancer . Surg Oncol Clin N Am. 2003 Jul;12(3):561-83
  82. Deraco M., Kusamura S., Casali P. Peritonectomy and Intra Peritoneal hyperthermic perfusion (IPHP): a promising strategy to the treat patients affected by peritoneal mesothelioma. Annals of Surgical Oncology 2003, suppl. 10 (1): S65.
  83. Deraco M., Kusamura S., Gronchi A. Peritonectomy and Intra Peritoneal hyperthermic perfusion (IPHP): a strategy that confirmed its efficacy in patients with pseudomyxoma peritonei. Annals of Surgical Oncology 2003, suppl. 10 (1): S67.
  84. Guadagni S., Santinami M., Patuzzo R., Pilati P.L., Miotto D., Deraco M., Rossi C.R., Fiorentini G., Di Filippo F., Valenti M., Amicucci G. Hypoxic pelvic amd limb perfusion with melphalan and mitomycin C for recurrent limb melanoma: a pilot study. Melanoma Research 2003, 13: 51-58.
  85. Cavaliere F., Perri P., Rossi C.R., Pilati P.L., De Simone M., Vaira M., Deraco M., Aloe S., Di Filippo S.and Di Filippo F. Sitilo Experience on Peritoneal Carcinomatosis from Colorectal Cancer: Clinical Prognostic Features.J. Exp. Clin. Cancer Research S Dec;22(4):.29-33
  86. Deraco Marcello, M.D.1, De Simone Michele M.D.2, Rossi Carlor Riccardo M.D.3, Cavaliere Francesco M.D.4, Difilippo Franco M.D.4, Scuderi Stefano, M.D. 5, Pilatti Pierluigi M.D.3 and Shigeki Kusamura M.D.6 An Italian multicentric phase II study on Peritonectomy and Intra Peritoneal Hyperthermic Perfusion (IPHP) to treat patients with Peritoneal Mesothelioma. J. of Exp. Clin. Cancer Res.2003 S Dec;22(4):.41-45
  87. Deraco Marcello, M.D.1, De Simone Michele M.D.2, Rossi Carlo Riccardo M.D.3, Cavaliere Francesco M.D.4, Difilippo Franco M.D.4, Pilati Pierluigi M.D.3 and Shigeki Kusamura M.D.6 An Italian multicentric phase II study on Peritonectomy and Intra Peritoneal Hyperthermic Perfusion (IPHP) to treat patients with Pseudomyxoma Peritonei.J. of Exp. Clin. Cancer Res. 2003 S Dec;22(4):.35-39
  88. Kusamura S., Deraco M., Baratti D., Inglese M:G:, Costanzo P., Favaro M., Manzi R., Gavazzi C. Cytoreductive Surgery followed by Intra Peritoneal Hyperthermic Perfusion in the treatment of peritoneal surface malignancies: Morbidity and Mortality with Closed Abdomen Technique. J. of Exp. Clin. Cancer Res. 2003 S Dec;22(4):.207-212
  89. Di Filippo F., Garinei R., Anzà M., Cavaliere F., Giannarelli D., Cagol P.P:, Rossi C.R., Santinami M., Deraco M., Botti C., Perri P., Di Filippo S., Piarulli L., Bruno P. Doxorubicin in Isolated Limb Perfusion in the treatment of advanced Limb Soft Tissue Sarcoma. J. of Exp. Clin. Cancer Res. 2003 S Dec;22(4):. 81-87
  90. Rossi CR, Deraco M, De Simone M, Mocellin S, Pilati P, Foletto M, Cavaliere F, Kusamura S, Gronchi A, Lise M . Hyperthermic intraperitoneal intraoperative chemotherapy after cytoreductive surgery for the treatment of abdominal sarcomatosis: clinical outcome and prognostic factors in 60 consecutive patients. Cancer. 2004 May 1;100(9):1943-50
  91. Glehen O, Kwiatkowski F, Sugarbaker PH, Elias D, Levine EA, De Simone M, Barone R, Yonemura Y, Cavaliere F, Quenet F, Gutman M, Tentes AA, Lorimier G, Bernard JL, Bereder JM, Porcheron J, Gomez-Portilla A, Shen P, Deraco M, Rat P. Cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for the management of peritoneal carcinomatosis from colorectal cancer: a multi-institutional study. J Clin Oncol. 2004 Aug 15;22(16):3284-92
  92. Kusamura S, Raspagliesi F, Baratti D, Gronchi A, Casali P, Deraco M. Uterine sarcoma treated by cytoreductive surgery and intraperitoneal hyperthermic perfusion: a feasiblity study. J Chemother. 2004 Nov;16 Suppl 5:19-22
  93. Nonaka D, Kusamura S, Dario Baratti, Casali P, Younan R, Deraco M. Pseudomyxoma Peritonei Treated by Peritonectomy and Intraperitoneal Hyperthermic Perfusion: A Clinicopathologic study of 42 cases treated at a single institution. BJS submitted
  94. Nonaka D, Kusamura S, Baratti D, Casali P, Rosai J, Younan R and Deraco M. Diffuse Malignant Mesothelioma of the Peritoneum: a clinicopathologic study of 35 cases treated locoregionally at a single institution. Cancer. 2005 Nov 15;104(10):2181-8.
  95. Younan R, Kusamura S, Baratti D, Costanzo P, Favaro M, Gavazzi C, and Deraco M. Bowel complications and safety of performing a primary anastomoses during peritonectomy and closed-technique hyperthermic intraperitoneal chemotherapy perfusion. Annals of Surgical Oncology. Ann Surg Oncol. 2005 set 21.
  96. Marcello Deraco, M.D., Daisuke Nonaka, M.D., Dario Baratti, M.D., Paolo Casali, M.D., Juan Rosai, M.D., Rami Younan M.D. and Shigeki Kusamura, M.D. Prognostic analysis of clinicopathologic factors in 49 patients with diffuse malignant peritoneal mesothelioma treated with cytoreductive surgery and intraperitoneal hyperthermic perfusion. Annals of Surgical Oncology. Annals of Surgical Oncology, 13(2): 229)237
  97. M Deraco, M.D., NS Turhal, M.D., R Younan, M.D., M Zanna , M.D., MG Inglese, M.D., L Mariani, Ph.D., S Lo Vullo, Ph.D. and M Santinami, M.D Isolated limb perfusion for stage III melanoma of the extremities: results from a prospective series of 260 patients. Annals of Surgical Oncology. In Press.
  98. Shigeki Kusamura, M.D., Rami Younan, M.D., Dario Baratti, M.D., Pasqualina Costanzo M.D., Miriam Favaro M.D., Cecilia Gavazzi M.D., and Marcello Deraco M.D. Cytoreductive surgery followed by Intraperitoneal Hyperthermic Perfusion in the treatment of Peritoneal Surface Malignancies: analysis of morbidity and mortality in 209 cases treated with closed abdomen technique. Cancer. 2006 Mar 1;106(5):1144-53Cancer in Press.
  99. Raspagliesi F, Kusamura S, Campos Torres JC, de Souza GA, Ditto A, Zanaboni F, Younan R, Baratti D, Mariani L, Laterza B, Deraco M. Cytoreduction combined with intraperitoneal hyperthermic perfusion chemotherapy in advanced/recurrent ovarian cancer patients: The experience of National Cancer Institute of Milan. Eur J Surg Oncol. 2006 Apr 15
  100. Iaffaioli RV, Facchini G, Tortoriello A, Crovella F, Romano G, Formato R, Santangelo M, Barletta E, Fiore F, Iaccarino V, Memoli B, D'Angelo R, Pilati PL, Rossi R, Guadagni S, Deraco M, Pignata S, Daniele B, Rosati G, Massidda B, Mantovani G, Di Salvo E, Marzano N, Memeo V, Parisi V, Mallarini G, Colucci G. Stop Flow in abdominal and pelvic cancer relapses Front Biosci. 2006 May 1;11:1284-8.
  101. Nonaka D, Kusamura S, Baratti D, Casali P, Younan R, Deraco M. CDX-2 expression in pseudomyxoma peritonei: a clinicopathological study of 42 cases. Histopathology. 2006 Oct;49(4):381-7.
  102. Esquivel J, Sticca R, Sugarbaker P, Levine E, Yan TD, Alexander R, Baratti D, Bartlett D, Barone R, Barrios P, Bieligk S, Bretcha-Boix P, Chang CK, Chu F, Chu Q, Daniel S, de Bree E, Deraco M, Dominguez-Parra L, Elias D, Flynn R, Foster J, Garofalo A, Gilly FN, Glehen O, Gomez-Portilla A, Gonzalez-Bayon L, Gonzalez-Moreno S, Goodman M, Gushchin V, Hanna N, Hartmann J, Harrison L, Hoefer R, Kane J, Kecmanovic D, Kelley S, Kuhn J, Lamont J, Lange J, Li B, Loggie B, Mahteme H, Mann G, Martin R, Misih RA, Moran B, Morris D, Onate-Ocana L, Petrelli N, Philippe G, Pingpank J, Pitroff A, Piso P, Quinones M, Riley L, Rutstein L, Saha S, Alrawi S, Sardi A, Schneebaum S, Shen P, Shibata D, Spellman J, Stojadinovic A, Stewart J, Torres-Melero J, Tuttle T, Verwaal V, Villar J, Wilkinson N, Younan R, Zeh H, Zoetmulder F, Sebbag G; Society of Surgical Oncology Annual Meeting. Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of peritoneal surface malignancies of colonic origin: a consensus statement. Society of Surgical Oncology. Ann Surg Oncol. 2007 Jan;14(1):128-33. Epub 2006 Oct 28. No abstract available.
  103. Pennacchioli E, Deraco M, Mariani L, Fiore M, Mussi C, Collini P, Olmi P, Casali PG, Santinami M, Gronchi A. Advanced extremity soft tissue sarcoma: prognostic effect of isolated limb perfusion in a series of 88 patients treated at a single institution. Ann Surg Oncol. 2007 Feb;14(2):553-9. Epub 2006 Nov 23.
  104. Baratti D, Kusamura S, Martinetti A, Seregni E, Oliva DG, Laterza B, Deraco M. Circulating CA125 in Patients with Peritoneal Mesothelioma Treated with Cytoreductive Surgery and Intraperitoneal Hyperthermic Perfusion. Ann Surg Oncol. 2007 Feb;14(2):500-8. Epub 2006 Dec 6.
  105. La Manna G, Virzi S, Deraco M, Capelli I, Accorsi A, Dalmastri V, Comai G, Bonomi S, Grassi A, Selva S, Feliciangeli G, Scolari M, Stefoni S. Tubular dysfunction after peritonectomy and chemohyperthermic treatment with cisplatin. In Vivo. 2006 Nov-Dec;20(6A):703-6.
  106. Cavaliere F, Valle M, De Simone M, Deraco M, Rossi CR, Di Filippo F, Verzi S, Giannarelli D, Perri P, Pilati PL, Vaira M, Di Filippo S, Garofalo A. 120 peritoneal carcinomatoses from colorectal cancer treated with peritonectomy and intra-abdominal chemohyperthermia: a S.I.T.I.L.O. multicentric study. In Vivo. 2006 Nov-Dec;20(6A):747-50
  107. Deraco M, Kusamura S, Laterza B, Favaro M, Fumagalli L, Costanzo P, Baratti D. Cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (HIPEC) in the treatment of pseudomyxoma peritonei: ten years experience in a single center. In Vivo. 2006 Nov-Dec;20(6A):773-6.
  108. Deraco M, Baratti D, Zaffaroni N, Cabras AD, Kusamura S.Advances in clinical research and management of diffuse peritoneal mesothelioma. Recent Results Cancer Res. 2007;169:137-55.
  109. Baratti D, Kusamura S, Martinetti A, Seregni E, Laterza B, Oliva DG, Deraco M. Prognostic value of circulating tumor markers in patients with pseudomyxoma peritonei treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Ann Surg Oncol. 2007 Aug;14(8):2300-8. Epub 2007 May 18.
  110. Kusamura S, Baratti D, Younan R, Laterza B, Oliva GD, Costanzo P, Favaro M, Gavazzi C, Grosso F, Deraco M: Impact of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy on systemic toxicity.Ann Surg Oncol. 2007 Sep;14(9):2550-8. Epub 2007 Jun 9.
  111. Deraco M, Baratti D, Kusamura S Morbidity and quality of life following cytoreduction and HIPEC.Cancer Treat Res. 2007;134:403-18.
  112. Baratti D, Kusamura S, Nonaka D, Oliva GD, Laterza B, Deraco M. Multicystic and well-differentiated papillary peritoneal mesothelioma treated by surgical cytoreduction and hyperthermic intra-peritoneal chemotherapy (HIPEC). Ann Surg Oncol. 2007 Oct;14(10):2790-7. Epub 2007 Jul 28.
  113. Kusamura S, Baratti D, Antonucci A, Younan R, Laterza B, Oliva GD, Gavazzi C, Deraco M: Incidence of Postoperative Pancreatic Fistula and Hyperamylasemia after Cytoreductive surgery and Hyperthermic Intraperitoneal Chemotherapy. Ann Surg Oncol. 2007 Dec;14(12):3443-52. Epub 2007 Oct 2.
  114. Dario Baratti, Shigeki Kusamura, Daisuke Nonaka, Martin Langer, Salvatore Andreola, Miriam Favaro, Cecilia Gavazzi, Barbara Laterza, MD,1 and Marcello Deraco, Pseudomyxoma Peritonei: Clinical Pathological and Biological Prognostic Factors in Patients Treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Annals of Surgical Oncology 2007 DOI: 10.1245/s10434-007-9691-2

Milan, November 2007